Products

Potassium tert-butoxide, is a widely used strong base and reagent in organic chemistry. It is obtained by reacting potassium hydroxide with tert-butanol, resulting in the chemical formula KOtBu. This white or offwhite crystalline solid demonstrates high solubility in polar solvents like alcohols, ethers, and dimethyl sulfoxide (DMSO). As a strong base, KOtBu finds primary application in deprotonation reactions within organic synthesis. It serves as a nucleophilic catalyst and strong base in various reactions, including, elimination, and condensation reactions. Its versatility allows it to promote reactions such as dehydrohalogenation, aldol condensation, Claisen condensation, and the Williamson ether synthesis. Within the pharmaceutical industry, KOtBu plays a pivotal role as a reagent in diverse organic synthesis processes. Its basicity and nucleophilicity make it an invaluable tool for the preparation of active pharmaceutical intermediates, enabling the creation of essential compounds in pharmaceutical research and development with different activities like antineoplastic, anti-hypertensive, neuroprotectant, anticoagulant, antihistaminic, antibacterial.

2-Phenoxyethanol Multi-Compendial (Excipient Grade) is a preservative that meets USP-NF, EP, and BP monographs. It is commonly used in dermatological products like sunscreen and skin creams, as well as in vaccines and pharmaceuticals. Known for its bactericidal and bacteriostatic properties, it is effective against a broad spectrum of gram-negative and gram-positive bacteria, and to a lesser extent, against yeast and mold. With its low toxicity, 2-Phenoxyethanol is valued in pharmaceutical applications. It is stable, non-reactive, and soluble in both water and oil. Typically used at a concentration of 5 mg/ml (0.5%) in vaccines, it is often combined with another preservative to enhance effectiveness. Recognized globally, it has monographs in the European (EP), British (BP), and United States Pharmacopeias (USP).

Actylis’ GMP Sucrose is a highly purified form of sucrose critical in the biopharmaceutical manufacturing of a number of therapeutic large molecules such as proteins, peptides, monoclonal antibodies, Antibody-Drug Conjugates (ADCs), vaccines and Cell & Gene Therapeutics. Low endotoxin sucrose mainly acts as a stabilizer and a preservative in biopharmaceutical formulations. It is preferred over other saccharides due to complexity and criticality of biopharmaceutical manufacturing parameters. Our GMP multi-compendial Low Endotoxin Sucrose conforms to USP-NF, EP and JP monographs.

Phenol is used as an antiseptic, preservative, and intermediate in pharmaceutical manufacturing. In liquid form, it is essential for controlled formulations and synthesis. Pharmaceutical-grade phenol ensures consistent purity for safe applications.

Ethyl acetate is a moderately polar, biodegradable solvent used in API synthesis, crystallization, and purification. In biopharma, it is applied in extraction and formulation processes, offering a favorable safety profile and ease of removal due to its volatility.

NMP is a solvent commonly used in pharmaceutical synthesis, drug formulation, and polymer processing. In biopharma, it supports the development of sustained-release systems, though its use is tightly regulated due to reproductive toxicity concerns.

IPA is an essential solvent and disinfectant in pharmaceutical and biopharmaceutical industries. It is widely used for cleaning, sterilization, and formulation processes, valued for its antimicrobial activity and volatility.

(Bromomethyl)-Cyclopropane is a liquid chemical used as an API intermediate in both API manufacturing and pharma and nutraceuticals. It plays a key role in the synthesis of active pharmaceutical ingredients, aiding in the development of various therapeutic products. This compound is essential for the production of key intermediates in pharmaceutical applications.

Dimethyl Sulfoxide (DMSO) is a highly polar solvent used in pharmaceuticals for solubilizing poorly water-soluble drugs, cryopreservation of cells in biopharma, and as a carrier in transdermal delivery systems. Its strong solvating power and biocompatibility make it versatile, though controlled due to safety considerations.

THF is a solvent used in API synthesis, purification, and polymer-based drug delivery. In biopharma, it supports the preparation of biodegradable polymers for controlled-release systems. Its use is regulated due to volatility and potential toxicity.

Dextromethorphan USP, containing the chemical compound dextromethorphan, serves over-the-counter (OTC) functions within pharmaceuticals and nutraceuticals. Classified as an active pharmaceutical ingredient (API) under pharmaceutical actives and precursors within pharmaceuticals and nutraceuticals, it is commonly used in various formulations due to its therapeutic properties.

n-Hexane is a solvent used in pharmaceutical extraction and purification, particularly for lipid-based materials. Due to its volatility and toxicity, residual levels in drug products are tightly controlled.

Acetone is a volatile, water-miscible solvent widely used in pharmaceutical production and bioprocessing. It serves as an extraction medium, cleaning agent, and process solvent, valued for its rapid evaporation and low toxicity, with strict limits on residual levels.

N-heptane is used as a non-polar solvent in pharma crystallization and purification processes. It supports separation of APIs and intermediates. High-purity grades guarantee minimal impurities for reliable performance.

DCM is a widely used solvent in pharma for extraction, purification, and synthesis of APIs. Its volatility and excellent solvency make it essential in chromatography and crystallization. Pharmaceutical-grade DCM ensures reliable performance with low residual impurities.